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Why You Should Trust Your “GUT FEELING” - Importance & Awesomeness of Bacteria - FutureIQ

4,487 views Wait, is this logic right? • Aug 09, 2024
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Slog Reference: Bacteria are Awesome

Description

Bacteria are way cooler than you can imagine them to be. You are composed of trillions of them and they work in coordination with your body to keep you alive. Without bacteria, a lot of things will break down, causing chaos in your body and in a world that is heavily dependent on microscopic creatures for survival.

Let's take our time to appreciate the awesome nature of bacteria and the brilliant scientific discoveries that may allow us to take advantage of these for various treatments and climate change.

Hope you enjoyed FutureIQ by Navin Kabra and Shrikant Joshi. Do hit us up on Twitter:
@ngkabra http://twitter.com/ngkabra
@shrikant https://twitter.com/shrikant

Listen it on the podcast provider of your choice: https://tapthe.link/FutureIQRSS
Watch other episodes of The FutureIQ podcast: https://www.youtube.com/playlist?list=PLAppTB0r5_TaYueZ0adD42Wiw5X-wTE4v

More videos for you:
Aryan migration theory: https://youtu.be/9AxXwYGgWK4
Theory of evolution: https://youtu.be/-tDvXOatH_s

Sources:
Gut microbe: https://en.wikipedia.org/wiki/Gut_microbiota
Gut-brain axis: https://en.wikipedia.org/wiki/Gut%E2%80%93brain_axis
Composition of feces: https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-13-1-45
Skin microbiome: https://www.webmd.com/skin-problems-and-treatments/skin-microbiome
Antibiotics: https://www.sciencedirect.com/science/article/pii/S1369527419300190
Bacteria and autism: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264285/
Bacteria causing hangovers: https://en.wikipedia.org/wiki/Auto-brewery_syndrome
Bacteria preventing hangovers: https://zbiotics.com/
Bacteria preventing cavities: https://www.astralcodexten.com/p/defying-cavity-lantern-bioworks-faq
Bacteria into storage disk: https://www.nature.com/articles/nature23017

Chapters:
00:00 Introduction
01:00 The goodness of bacteria
03:13 Life & bacteria
04:40 Mitochondria & eve gene
07:30 Gut bacteria
09:14 Bacteria deciding your mood
12:00 Detoxification gut bacteria health
15:30 Fecal transplants
19:30 Bacteria on skin
20:30 Climate change and other implications

#futureiq #bacteria #goodbacteria

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Transcript

we think of bacteria as dangerous organisms to be destroyed but did you know that you are alive because bacteria make it possible life cannot start without bacteria not a single cell in your body can exist without bacteria and when you die it will cause serious problems to the world if bacteria don't do their thing and many many things in our life would just stop working without the bacteria not just that h but we are finding fascinating new uses for bacteria and those uses work so well that we are trying to create even new bacteria to do interesting things for us okay didn't the scientists in every sci-fi movie advise against it yes that is part of
the problem every sci-fi movie just assumes that bacteria are the villain and that's a mistake okay they have been unfairly villainized most bacteria are good okay so let's try to explain the goodness of bacteria okay okay first let's start with the obvious right okay all decomposition is happening because of bacteria right the food you throw away the dead bodies right everything gets broken down and goes back to the dust and soil because of bacteria if not think of what could happen right yeah but all fermentation is because of yeast and bacteria okay that's definitely good bacteria no thei for you no lassi no cheese no IDI Dosa right those weren't the food and drink items I was thinking
of when you said fermentation no beer no wine okay more like yes and no soy sauce okay yeah but let me come to the more interesting ones that you had never heard about okay rain cannot form without bacteria rain yes this is new discoveries that the water vapor in the clouds needs seeds to condense upon and that happens due to bacteria in your fridge water converting to ice needs bacteria okay wait so when you go in the first train and you know drink it straight from the source you're actually consuming bacteria yes of course I mean you you are already bacteria okay your stomach has 100 trillion bacteria of thousand different species okay okay we'll come
to that all right all right but let's think of simpler things okay most antibiotics were discovered because of bacteria right bacteria fighting bacteria okay bacteria fighting bacteria yes right because they're fighting each other obviously they're at a war with each other and bacteria a figures out how to beat bacteria B and we use that technique and that becomes our antibiotic right but but more importantly not a single cell in your body can exist without bacteria okay let's think about the basics okay of Cell Biology okay all proteins and most other things in a Cell right they come from six elements carbon hydrogen nitrogen oxygen phosphorus and sulfur phosphorus and sulfur yeah they are needed in every protein so now hydrogen
we directly take from the water okay that's good oxygen we take from the air all right carbon phosphorus and sulfur we get all of those from Plants true okay by eating plants that's where we get our carbohydrates from phosphorus and sulfur also where do plants get that from okay plants get carbon from the air from carbon dioxide during photosynthesis they extract it correct right they take phosphor from the C okay yeah nitrogen neither us nor plants nobody knows how to take nitrogen okay the only things on earth that know how to convert atmospheric nitrogen into ammonia in a form which plants can absorb are bacteria okay without bacteria no ammonia no plants no animals no humans
nobody okay ongoing on a daily basis yeah of course okay so no bacteria no new cells can form no bacteria no us essentially well that is true in a different sense also huh okay mitochondria huh you the PowerHouse of the cell correct it's the only thing from biology that I remember mitochondria is the PowerHouse of the cell what about mitochondria and bacteria though mitochondria are bacteria okay what what happened is that two billion years ago one of your ancestors which was like a eukariotic cell floating around at that time high grandpa that cell noticed a particular bacterium which was extremely good very efficient at converting oxygen to energy okay and what this your ancestor decided
to do Grandpa or Grandma grandma I'll tell you why okay is to enslave that bacteria engulf it put it inside and then use it as the PowerHouse of the cell for the rest of 2 billion years and toally UK carotic cell great great great whatever Grandma consumed a battery and kept it running kept it running not just that huh but every time you reproduce right every time a cell divides that mitochondria that bacteria in there which has its own independent DNA by the way oh okay so your DNA and the mitochondria DNA are different things so that also divides okay not just that but when you are born conceived right you get half your DNA
from your mom and half from your dad yeah but that's not true of the mitochondria you get your entire mitochondria only from your mom that's why Grandma okay that's why Grandma but the thing is that you are getting an identical copy except for small mutations right so you are not getting any mitochondria from your dad you're getting it only from your mom who got it from her mom who got it from her mom so you can create an unbroken chain of mitochondrial DNA all the way down to that eukaryotic cell no well I mean we don't know about that probably but there is believed to be one prehistoric woman or humanoid called The ancestral Eve and all the mitochondria
of all the 8 billion humans on Earth today are derived from that one person and there is of course mutations happening along the way so it won't be the exact same but I I see no but it is from that one person right not from like 100 different people one person give us all our mitochondria okay the Earth Mother are our slave bacteria which are there in every cell and we couldn't do any energetic thing anything in fact without our pet bacteria wow wow so let's talk about the other bacteria in your body okay okay your gut which means primarily the intestine contains 100 trillion bacteria of a thousand different species that's a lot right
they're sitting there and they are a vital part of the digestion in your body okay in fact 60% of the dry mass of [ __ ] is bacteria okay but because this is a respectable channel for the rest of the episode we are going to refer to it as fishes but we are going to talk about fishes quite a lot now these gut bacteria okay by the way they have 100 times as many genes as you do okay and they are unique to you so the whole you know composition of different types of bacteria of this thousand different types right is unique to you as an individual which is different from her and different for me like a bacterial
fingerprint of SCE absolutely there is a bacterial fingerprint in your body and it controls a lot of things let's go through those right first of all we can't digest milk without the help of bacteria okay and this includes mother's milk okay you wouldn't be able to digest your mother's milk without bacteria okay so you have bacteria from Des okay okay second is that they synthesize some of the most important vitamins needed Vitamin B and vitamin K are which are necessary and they are created by bacteria in your stomach as a byproduct of digestion okay interesting the third and important thing they do is they break down the fiber that you are consuming M so basically they are
creating feces yes which is okay fine that's what yeah so okay here is where it gets interesting okay what we are recently discovering is that your gut along with this colony of bacteria when the bacteria when they break down fiber they break them down into short chain fatty acids okay the details are not important as CFA short chain fatty acids okay what what do they what do they do they control a large number of things in your body okay they control appetite they control metabolism they control your mood inflammation immune response basically we have suddenly discovered that your stomach plus bacteria are acting like an endocrine organ and the scfas are acting like a hormone which it goes into your
bloodstream it goes all over your body including your brain and heart and so on and it is a signal that is controlling in many different behaviors like I said first of all these are what are controlling your appetite okay okay these are what are also controlling your metabolism which means how much are you converting the food into fat and how much are you burning off okay these control inflammation okay uh and the immune response so your immune system can go into higher gear or lower gear depending on what your gut bacteria are doing and what you are eating okay oh it goes to your brain and it controls your mood okay so what you're eating and what your gut bacteria are
doing and the composition of the gut bacteria can decide whether you are going to get depressed or not okay what there is actual research showing that identical twins yeah okay one is obese and the other is not when they checked the gut bacteria they found that the composition of gut bacteria was very different obviously their genes are the same right they're identical twins yeah but one out of the pair of many pairs in this research was getting obese and the reason is because they had the wrong gut bacteria not just that but when they took some of these gut bacteria and put it into the other twin that twin started gaining weight okay hold on I was I was
going to ask you if that was possible but it seems it is possible I will ask you how later but first first does this mean that all the Modern Health gurus who talk about detoxification of your gut and who promise all kinds of health benefits from this detoxification are they right well it's a tricky question okay the following statement is very true okay that what you eat and your gut health affects many many other parts of your body including your mood and your sleep and so on mhm but detoxification is not really a scientific word they're just making it up as they go along most probably they are killing your good gut bacteria through all of those and causing more
damage okay so be careful because you don't want a clean gut with no bacteria you will die or at the very least you will just cause so many problems to your body that you don't want to go there right yeah we've just established no bacteria no human no no life no whatever exactly but then is there a scientific way to ensure that you know I maintain a healthy gut bacterial fingerprint right so let us first understand what is happening to your gut bacteria what affects and how right okay so by the way this whole thing is called the gut body brain axis right because your gut affects your body and your brain and the reverse is also true okay okay if you
eat a high fiber diet it increases the scfa bacteria so that signaling that is happening short chain fatty acids causing bacteria on the other hand if you eat high fat diet those bacteria decrease okay okay if you eat artificial sweeteners they disrupt some of the G bacteria and as a result they disrupt normal glucose intolerance okay okay if you are under stress the gut bacteria activity decreases okay if you take antibiotics of course antibiotic it means something that kills bacteria so after a single dose of antibiotic there is 30% reduction in gut bacteria at least in one particular research that they did and if you take a full course the effect can sometimes persist for months or even
two years in one particular case right ouch okay if you exercise the microbial diversity in your gut increases okay okay if your sleep gets disrupted the microbes go down okay so now you can think of what all is going on in your body yeah right and all of these things affect your gut bacteria H and that affects the rest of your body right so what I have just said was basic basic basic yeah you know advice I was just thinking of that what you basically told us is to eat fibrous foods do lots of exercise sleep well and at night and don't eat artificial sugar or Sweet avoid junk food and avoid junk food fatty food right the connection is there
through the gut bacteria and it is not affecting just your stomach it is not affecting just your weight it is affecting your mood it is affecting a whole bunch of things I was hoping for a short oh yes there is a shortcut why do you think of it feal transplants sorry what you have bad habits as a result you have bad gut bacteria I have good habits I have good gut bacteria so take my fishes put it in your stomach those bacteria will improve your stomach are you kidding me I am not kidding this is a real scientific actual me heard FDA approved okay listen I take a lot of your fishies on every single
episode this better be true this is true of course they do it a little more nicely they take the fishes and then they do processing on it and get rid of a whole bunch of nasty things and they just keep the dry mass and they make it like really dry and they put it in a capsule so that when you if nobody told you anything about it you would not realize that you're eating someone's fishes okay eat no you take the capsule and you drink water after it okay yeah and I am telling you after this if you have constipation it reduces if you have irritable bowel syndrome it reduces if you have multiple sclerosis there is
research showing it reduces if you have Parkinson's there are some early signs showing it reduces if you have ulcerative colitis it reduces if you have anti biotic resistant CI bacteria okay that's like a really really nasty stomach infection that just refuses to go away feal transplant has 85 to 90% efficacy right okay human fishes has been regulated as an experimental drug since 2013 in the US there are lots of people who have done this and have benefited from it I can send you links to Twitter threads of first person accounts if you want want right trials are underway for feal transplant as a cancer treatment okay okay because there is a protein in your body which blocks your immune system
from killing cancer cells and that causes cancer right as a result there is a therapy which blocks that protein so that the protein isn't able to block your immune system so that you're immune system can kill the cancer cells and your cancer gets better yeah there are some patients for whom this therapy doesn't work okay except after taking feal transplants it starts working there's a trial underway it is not yet approved but autism okay there is some studies in Arizona State and some studies in China and a few other things where it has been shown that feal transplants reduce the symptoms of autism okay this one is a really huge claim because autism is a
neurodevelopmental disorder yes and uh although we spoke about the gut body brain axis I am a little skeptical of this yes this is not yet you know fully proven but promising studies so far okay okay it is a study I'll definitely have to keep an eye out on regardless of anything and everything else but ah feal matter transplant sounds so no let's talk about let's talk about something else right like please let's let's talk about something else because the the very I I understand the novelty of it I understand the idea behind it I understand that it's basically taking your gut bacterial fingerprint and essentially putting it in another person so theoretically it makes sense that it
would work it's just the feal part of it sounds a little yeah no let's talk about something else right like your glowing skin second highest concentration of bacteria on us is on our skin again thousand different types of bacteria on our skin they protect us from other bad bacteria I mean before the bacteria can enter these ones fight them off and kill them okay they help our immune system to fight infections right they help in healing wounds they help in controlling the inflammation I told you bacteria are good at helping us control inflammation okay so again don't overdo the cleaning of your skin with antimicrobials and kills 99% of bacteria 99% of bacteria are necessary for you to survive okay so
that's one way to put yeah from what you've described so far it looks like bacteria are essentially The Cure All the Panacea to everything can bacteria solve World Peace well I don't know probably not World Peace but climate change possibly very likely right the thing is that if there is an oil spill one of the techniques we have for cleaning up oil spills is bacteria okay bacteria yes so when the Exxon W as oil spill right fertilizers were added to some of the beaches that produced appropriate bacteria and those bacteria go and eat up the hydrocarbons of the oil and break it down in 2010 the deep water Horizon oil spill right bacteria degraded 50% of
the hydrocarbons in 4 months okay nice okay sewage treatment okay bacteria can be used to remove 90% of the organic matter when you are treating sewage right if you take a typical sewage plant that handles 100 million gallons per day that uses 600 pound of bacteria to treat the organic sewage in there 600 lb for 100 million gallons that's an interesting ratio yeah all right so uh in mines right when you have to recover gold or Paladium or Copper from The Ore right currently we use chemicals for that right but bacteria are showing promise as an eco-friendly way of extracting these metals from ores okay interesting in clothes a lot of the colors on your clothes are again
chemicals which are bad for the climate and bacteria are an eco-friendly way of dying textiles that's Dy iing yes you know I'm talking about all these interesting uses we are finding for bacteria bacterial pesticides again e friendly pesticides compared to the chemicals that we are uh using right now right selfhealing bio concrete okay okay when you create concrete you mix in these specific bacteria along with some calcium lactate food source for the bacteria okay so that when cracks form these bacteria activate they start eating the calcium lactate and produce Limestone as a byproduct which fills in the crack and cements it okay self steing cement the cement is alive yes okay most molecular biology requires bacteria right I
already said that 2/3 of all antibiotics used clinically were discovered with the help of bacteria but when we are doing research on genes enzymes metabolic pathways and all of that we first do that research in bacteria and then what we learn from that we apply in other areas right interesting uh in fact uh because of their importance in research we have bacterial Banks okay bacterial Banks as you know deposit bacteria and take out bacteria absolutely I mean they're not called Banks they're called biological research centers but basically if you're a researcher and you're looking for a particular kind of bacteria you go to the bank and check out that bacteria hello can you send me some eoli please
oh what do I have in exchange I can offer you Ty probably you don't want dius okay see again you are thinking of the wrong kind of bacteria think of the good bacteria and the good things they can do for you hangover anti-hangover bacteria there okay now I'm interested yes please there is a company which claims to sell this product where you have it before consuming alcohol and the bacteria which sit in your stomach and they do their thing and they prevent you from having a hangover I need details on this company right away permanently prevent cavities in your teeth through the use of bacteria there's a different company called Lantern bioworks which sells a
bunch of bacteria not affiliated just happen to know the name yes which you apply to your teeth and they say that those bacteria will form a colony in your teeth and they fight off the bad bacteria which give you cavities okay why didn't I know about them 6 months ago yeah also scientists also scientists have found a way to convert bacteria into a storage disc right they were able to store images and a little short movie into a bacterial colony and extract it later so point of this episode is stop thinking of bacteria as the enemies so I figured right they are necessary for life they are necessary for your good health and not not just that it is very likely that
they will save our planet right it is possible that they are the ones who are going to solve our plastic biodegradation problem and it is possible that when Ellen musk takes us to Mars bacteria are the ones that will terraform Mars and make it habitable for us Elon Musk isn't taking us anywhere other than on some wild ride but Crux of this episode bacteria are and pardon my friend the [ __ ] n future IQ we are bacteria in our own way